Camphor vs Tea Tree Oil for Skin: What the Evidence Covers

For acne-prone skin questions, tea tree oil is the only one of the two with published randomized trials, both using a 5 percent gel. Camphor oil has none that we found, and both are skin irritants at strength. We sell camphor oil as an aromatic material, so this is an evidence comparison, not a recommendation to apply either.

Camphor Essential Oil bottle

Camphor Essential Oil

Our own Camphor Essential Oil, in sizes from 0.5 oz to bulk.

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Who this comparison is for, and who it is not for

A reader who searches this comparison usually has a skin concern and two bottles in mind. The honest answer starts with a limit: we are a shop that sells one oil, and neither oil is sold here for a skin condition. Persistent acne, a rash, or anything that looks infected belongs with a dermatologist or primary care clinician, not with a bottle of essential oil. What we can do is lay out what the published studies examined for each oil, so you can see which claim has a study behind it and which does not. Our broader piece on the topic is Camphor Oil on Skin.

What is in each oil

Tea tree oil is defined by an international standard, ISO 4730, which sets ranges for its constituents. In a Colombian study that checked three batches against that standard, all three conformed and contained 30 to 40 percent terpinen-4-ol, the compound usually named as the one that matters in tea tree oil. That standard is the reason a buyer can reasonably ask a tea tree supplier for a specification. There is no equivalent for the oil that we sell.

White camphor oil is a fraction of the camphor-tree distillate. The Tisserand Institute notes that crystalline camphor is filtered out first and the remainder fractionated, and that the white fraction contains very little camphor (up to 9 percent, more typically 3 percent). So the camphor in a camphor-and-menthol skin product is not the same thing as camphor oil. Our Inside the Still page describes our white fraction. Our posted certificate lists physical constants and no GC/MS, so we cannot give a composition for the lot.

The tea tree trials, read carefully

Two trials get cited constantly. Their details are more useful than their headlines.

StudyDesignWhat it examinedWhat it reported
Bassett et al., 1990Single-blind randomized, 124 patients5% tea tree oil gel against 5% benzoyl peroxide lotion in mild to moderate acneBoth reduced inflamed and non-inflamed lesions; tea tree oil acted more slowly; fewer side effects with tea tree oil
Enshaieh et al., 2007Double-blind placebo-controlled, 60 patients, 45 days5% tea tree oil gel against placeboLesion count and severity index improved more than placebo (3.55 times and 5.75 times); side effects similar and tolerable

Look at what was tested: a formulated 5 percent gel, not oil from a bottle, in studies of a few dozen to about a hundred people. The first compared it with an established product and did not use a placebo. The second used a placebo but was small and short. Together they are encouraging and limited, which is how we would describe them to anyone. They are also the entire argument for putting tea tree ahead of camphor, so it matters that they are not large.

The camphor side of the ledger

Camphor has a very different evidence base. A title search of Europe PMC for camphor with acne, dermatitis or skin returned 15 records. We read the titles. None was a randomized trial of camphor oil for acne. Among them were:

Our position follows from that list. A seller who says camphor oil "is good for acne" has no trial to point to. That is why our acne article reports limited evidence rather than a benefit.

On OTC labels, camphor appears in skin products at set percentages. FDA's external analgesic monograph (M017) lists camphor at 0.1 to 3 percent in its lower-range group and at more than 3 and up to 11 percent in its cooling-sensation group. Those are regulatory facts about OTC drug products. Our oil is not one.

Irritation risk compared

Tea tree has the better-documented toxicology review. A 2006 review by Hammer and colleagues concluded that the oil is toxic if ingested in higher doses, can cause skin irritation at higher concentrations, and can trigger allergy in predisposed people, possibly through oxidation products that form with exposure to light and air. Its suggested precautions were to avoid ingestion, apply only diluted oil, and store the oil properly. The oxidation point has a practical consequence: a tea tree bottle that has sat open in a warm bathroom is not the same material it was.

Camphor skin irritation has no single review that we could open, but the labels of OTC camphor products give a picture. The Tiger Balm Ultra Strength label (11 percent synthetic camphor and 11 percent menthol) says not to apply to wounds or damaged or irritated skin, not to bandage, and to ask a healthcare professional first if pregnant, breast-feeding or having sensitive skin. It directs children 12 and under to consult a doctor.

The common thread: both oils belong on intact skin, diluted, patch-tested, and away from children. Our patch test guide and dilution guide cover the mechanics, and our Inside the Still page states that camphor is contraindicated for infants and young children.

Buying either one honestly

For tea tree, quality is a measurable problem. A 2015 chemometric study of 104 tea tree oils and commercial products found that 49 percent of the commercial products did not meet the ISO specifications, mostly through excess p-cymene (an oxidation marker) or depleted terpinenes. So the standard buyer's question for tea tree is "is it fresh and does it meet ISO 4730," and the answer should come from a lot report.

For camphor, the same logic applies in a different form: which fraction, which chemotype, and what does the GC/MS say. Ours is a white fraction in dark amber glass, 0.5 oz to 400 lb, in our shop, and the safrole result for each lot is available when you ask. It is not published, and the certificate we post does not cover composition. We would rather you know that before ordering than after.

Our verdict

For the fungus question that sometimes gets bundled into this comparison, see the toenail study explained. It examined a combination rub and says nothing regarding either oil alone.

Questions we get asked

Is tea tree oil stronger than camphor oil for skin?

Strength is not the right measure. Tea tree oil has two small randomized trials of a 5 percent gel; camphor oil has none that we found. Both can irritate.

Can I mix camphor and tea tree oil?

We do not recommend it for skin. Each has its own irritation profile, and combining them removes the one thing you can control, which is knowing what caused a reaction.

Is either safe on children's skin?

Not by our standards. Ask a pediatrician. Camphor is contraindicated for infants and young children on our own hazard page.

This article is an evidence review, not medical advice. For acne, rashes or infections, consult a dermatologist or physician.

Camphor Essential Oil bottle

Camphor Essential Oil

Camphor Essential Oil from our own shop, in sizes from 0.5 oz to bulk.

From $8.69

Shop Now →

Sources & Further Reading